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Nichi Glucan in Cancer and Infections

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Another study by Montelli et al (6) has concluded that the NK cell activity was significantly lower in a group of brain tumour victims in a familial manner (n=15) compared to healthy controls of similar parameters.

In spite of several advancements in the modern medicine, a total cure to Cancer has not yet been feasible due to several factors. The preventive aspects of Cancer, though include several measures such as lifestyle changes, food intake, avoidance of smoking etc, food supplements occupy a major portion.

There are many clinical and animal studies which have proven that Beta glucan increase immune response (1,2), increase apoptosis in colon cancer (3), increase NK cell activity (4), in Japan we found many consumers of the nichi Glucan came with an experience that they have started feeling healthier and that the frequency of them suffering from common cold has come down, we though of doing a study on evaluation of the nichi Glucan in several components of immune mechanisms of the body. To our surprise we found that the NK cells profile increases significantly when the study subjects consumed nichi Glucan regularly (See the graph)


Dr Imai et al of Saitama University, Japan(5) have proven in their study of 11 years that in a 3625 population community, those with a lower NK cell profile have more chances of becoming cancer victims compared to those who have a relatively higher NK cell profile. Correlating our finding that the nichi Glucan increases the NK cells profile and the study by Imai et al, it is becoming very clear that nichi Glucan could be an indispensable health supplement to every one to increase their immunity in terms of NK cells profile thereby preventing the occurence of viral infections and cancer.

References:

1. Thompson IJ, Oyston PC, Williamson DE, " Potential of the beta-glucans to enhance innate resistance to biological agents", Expert Rev Anti Infect Ther. 2010 Mar;8(3):339-52

2. Sang HM, Fotedar R, .Effects of dietary beta - 1,3 - glucan on the growth, survival, physiological and immune response of marron, Cherax tenuimanus (smith, 1912), Fish Shellfish Immunol. 2010 Feb 6

3. Kim MJ, Hong SY, Kim SK, Cheong C, Park HJ, Chun HK, Jang KH, Yoon BD, Kim CH,Kang SA, "Beta-Glucan enhanced apoptosis in human colon cancer cells SNU-C4", Nutr Res Pract. 2009 Fall;3(3):180-4. Epub 2009 Sep 30.

4. Imai K, Matsuyama S, Miyake S, Suga K, Nakachi K. "Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population". Lancet. 2000 25;356(9244):1795-9.

5. Montelli TC, Peracoli MT, Gabarra RC, Soares AM, Kurokawa CS, "Familial Cancer: depressed NK-cell cytotoxicity in healthy and cancer affected members", Arq Neurosiquiatr2001 59(1)